Could Probiotics help Treat Depression?
Depression and Microbiota
Depression is a state of low mood or loss of interest or pleasure in usual activities, often accompanied by changes in thinking and behavior. There is emerging evidence of a link between stress, mood disorders and gut microbiota. Early human studies suggest that altering the microbiota with beneficial bacteria, or probiotics, can lead to changes in brain function, as well as subjective reports of mood.
Psychobiotics Benefits for Depression
Recently, psychobiotics have been defined as live organisms that, when ingested in adequate amounts, produce a health benefit in patients suffering from psychiatric illness . Evidence is emerging of psychobiotic benefits in alleviating symptoms of depression. The intestinal microbial balance may alter the regulation of inflammatory responses and in so doing, may be involved in the modulation of mood and behavior.
Promising Research Results for Depression Probiotics Treatment
The influence of probiotics intake on the improvement of depression symptoms is supported by results from human studies. In one study, healthy volunteers received either a probiotic combination (Lactobacillus helveticus and Bifidobacterium longum) or placebo for 30 days. Those who received the probiotics reported lower stress levels and displayed beneficial psychological effects in healthy human volunteers. Furthermore, urinary free cortisol levels were significantly reduced by the probiotics, providing a potential mechanism for the improvement in psychological symptoms observed . Another study found that the consumption of a Lactobacillus casei -containing yogurt improved mood. One hundred and twenty-four healthy subjects with a mean age of 61.8 years consumed daily, either a L.casei –containing milk drink or a placebo for 3-weeks. Mood and cognition were measured at the beginning and after 10 and 20 days of consumption. The subjects that started the experiment with the lowest mood, responded selectively by reporting themselves as happy rather than depressed after taking the probiotics .
Conclusion: Depression and Probiotics Treatment
These studies encourage the consumption of the appropriate probiotics to alleviate sadness symptoms and support the sense of well-being. We found two products that contain the required probiotic strains – you are invited to click on the link to find the Depression Probiotics Supplements.
Quick Advice: What is the most recommended priobiotic supplement for depression?
Click on the link to see the answer: Jarrow Formulas Jarro-dophilus EPS, 120 Capsules.
Depression and Probiotics: Research Resources
1. Dinan TG, Stanton C, Cryan JF: Psychobiotics: a novel class of psychotropic. Biological psychiatry 2013, 74(10):720-726.
2. Messaoudi M, Lalonde R, Violle N, Javelot H, Desor D, Nejdi A, Bisson JF, Rougeot C, Pichelin M, Cazaubiel M et al: Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. The British journal of nutrition 2011, 105(5):755-764.
3. Benton D, Williams C, Brown A: Impact of consuming a milk drink containing a probiotic on mood and cognition. European journal of clinical nutrition 2007, 61(3):355-361.